Keep as concentrated solution.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1110008L20Rik antibody; Calcium uptake protein 2, mitochondrial; EF hand domain family; EF hand domain family A1; EF hand domain family A1 antibody; EF hand domain family, member A1; EF-hand domain family; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; EF-hand domain-containing family member A1 antibody; EFHA1 antibody; FLJ25016 antibody; FLJ34588 antibody; member A1 antibody; Smhs2 homolog; Smhs2 homolog antibody
Gene Aliases: 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; EFHA1; MICU2; RGD1309934; Smhs2