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Proteintech
EGR3 Polyclonal Antibody
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Product Details
26495-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EGR3 fusion protein Ag24152
Conjugate
Form
Liquid
Concentration
500 µg/mL
Amount
75 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MTGKLAEKLP VTMSSLLNQL PDNLYPEEIP SALNLFSGSS DSVVHYNQMA TENVMDIGLT NEKPNPELSY SGSFQPAPGN KTVTYLGKFA FDSPSNWCQD NIISLMSAGI LGVPPASGAL STQTSTASMV QPPQGDVEAM YPALPPYSNC GDLYSEPVSF HDPQGNPGLA YSPQDYQSAK PALDSN
Target Information
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Early growth response protein 3; EGR-3; immediate-early transcription factor; MGC138484; unnamed protein product; Zinc finger protein pilot
Gene Aliases: EGR-3; EGR3; PILOT
UniProt ID: (Human) Q06889
Entrez Gene ID: (Human) 1960
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
positive regulation of endothelial cell proliferation
cell migration involved in sprouting angiogenesis
regulation of transcription from RNA polymerase II promoter
neuromuscular synaptic transmission
peripheral nervous system development
muscle organ development
circadian rhythm
positive regulation of T cell differentiation in thymus
endothelial cell chemotaxis
cellular response to vascular endothelial growth factor stimulus
negative regulation of apoptotic process
cellular response to fibroblast growth factor stimulus
regulation of gamma-delta T cell differentiation
positive regulation of transcription from RNA polymerase II promoter
system development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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