Peptide sequence: ALPPYSNCGD LYSEPVSFHD PQGNPGLAYS PQDYQSAKPA LDSNLFPMIP
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Early growth response protein 3; EGR-3; MGC138484; Zinc finger protein pilot
Gene Aliases: EGR-3; EGR3; PILOT
UniProt ID: (Human) Q06889
Entrez Gene ID: (Human) 1960
Molecular Function: C2H2 zinc finger transcription factor