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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:4,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:400 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
EHHADH Fusion Protein Ag24237 (108-284 aa encoded by BC038948) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.29 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: GCHYRIAHA EAQVGLPEVT LGLLPGARGT QLLPRLTGVP AALDLITSGR RILADEALKL GILDKVVNSD PVEEAIRFAQ RVSDQPLESR RLCNKPIQSL PNMDSIFSEA LLKMRRQHPG CLAQEACVRA VQAAVQYPYE VGIKKEEELF LYLLQSGQAR ALQYAFFAER KANKWSTP (108-284 aa encoded by BC038948)
As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional protein; L-bifunctional protein, peroxisomal; LBP; MFE1; Multifunctional enzyme 1; PBE; Peroxisomal bifunctional enzyme; peroxisomal enoyl-CoA hydratase
Gene Aliases: ECHD; EHHADH; FRTS3; L-PBE; LBFP; LBP; PBFE
UniProt ID: (Human) Q08426
Entrez Gene ID: (Human) 1962
Molecular Function:
dehydrogenase
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