Immunogen sequence: VGNRAIRTEK IICRDVARGY ENVPIPCVNG VDGEPCPEDY KYISENCETS TMNIDRNITH LQHCTCVDDC SSSNCLCGQL SIRCWYDKDG RLLQEFNKIE PPLIFECNQA CSCWRNCKNR VVQSGIKVRL QLYRTAKMGW GVRALQTIPQ GTFICEYVGE LISDAEADVR EDDSYLFDLD NKDGEVYCID ARYYGNISRF INHLCDPNII PVRVFMLHQD LRFPRIAFFS SRDIRTGEEL GFDYGDRFWD IKSKYFTCQC GSEKCKHSAE AIALEQSRLA RLDPHPELLP ELGSLPPVNT; Positive Samples: U-937, 293T, Jurkat, MCF7, HepG2; Cellular Location: Chromosome, Nucleus
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.
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Protein Aliases: ankyrin repeat-containing protein; DKFZp686H08213; Euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G9A histone methyltransferase; H3 ly; H3-K9-Histone-Methyl-Transferase; H3-K9-HMTase 3; Histone H3-K9 methyltransferase 3; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; HLA-B associated transcript 8; HLA-B associated transcript 8, rat orthologue; HLA-B-associated transcript 8; Lysine N-methyltransferase 1C; NG36/G9a; Protein G9a
Gene Aliases: BAT8; C6orf30; D17Ertd710e; EHMT2; G9A; GAT8; KMT1C; NG36