Anti-Hu antibodies were originally isolated from a patient with paraneoplastic encephalomyelitis, a rare condition of selective neural tissue injury associated with small cell lung carcinoma. The antibodies bind specifically to antigens present exclusively in neuronal cells and are thus useful as markers of neuronal cells in tissue. The Hu antigen is an RNA-binding protein of the embryonic lethal abnormal visual (Elav) family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like neuronal protein 1; ELAV-like neuronal protein 1 isoform Hel-N2; ELAV-like protein 2; ELAV-like protein 4; ELAVL3; embryonic lethal, abnormal vision-like 2; Hu antigen D; HU-antigen B; HU-antigen D; HuB; HuD; Nervous system-specific RNA-binding protein Hel-N1; Nervous system-specific RNA-binding protein Mel-N1; Paraneoplastic encephalomyelitis antigen HuD; PLE21; RNA binding protein HuB; RNA-binding protein HUD3
Gene Aliases: Elav; Elav2; ELAVL2; ELAVL4; HEL-N1; HELN1; HUB; HUD; mel-N1; PNEM; r-HuD; RGD1561943