ELF4 is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. The protein acts synergistically with RUNX1 to transactivate the IL3 promoter. Also transactivates the PRF1 promoter in natural killer (NK) cells. This protein plays a role in the development and function of NK and NK T-cells and in innate immunity.
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Protein Aliases: E74-like factor 4; E74-like factor 4 (ets domain transcription factor); E74-like factor 4; myeloid elf-1-like factor; myeloid elf-1 like factor; ELF4; ETS-related transcription factor Elf-4; myeloid elf-1 like factor; Myeloid Elf-1-like factor
Gene Aliases: AV314029; BC042423; ELF4; ELFR; ENSMUSG00000053512; Gm9907; MEF; RGD1560743