This target displays homology in the following species: Mouse: 100%; Rat: 85%
ELF4 is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. The protein acts synergistically with RUNX1 to transactivate the IL3 promoter. Also transactivates the PRF1 promoter in natural killer (NK) cells. This protein plays a role in the development and function of NK and NK T-cells and in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E74-like factor 4; E74-like factor 4; myeloid elf-1-like factor; myeloid elf-1 like factor; elf4; ETS-related transcription factor Elf-4; myeloid elf-1 like factor; Myeloid Elf-1-like factor; name: ELF4; synonyms: ELFR; synonyms: MEF
Gene Aliases: AV314029; BC042423; Elf4; ENSMUSG00000053512; Gm9907; Mef; RGD1560743
UniProt ID: (Mouse) B1AY67