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Invitrogen
ELF5 Polyclonal Antibody
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Product Details
PA5-68805
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of mouse ELF5
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 85%; Horse: 92%; Human: 92%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Target Information
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E74-like factor 5; elf-5; Epithelium specific Ets-2; ETS-related transcription factor Elf-5
Gene Aliases: Elf5; ESE-2; ESE-5; ESE-5.
UniProt ID: (Mouse) Q8VDK3
Entrez Gene ID: (Mouse) 13711
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
ectodermal cell fate commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
ectoderm development
somatic stem cell population maintenance
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mammary gland epithelial cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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