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Immunogen sequence: ECDSTDDCIE HNIGPCSSVL DVGGAVTAVS VCPVLHPSQR YVVAVGLECG KICLYTWKKT DQVPEINDWT HCVETSQSQS HTLAIRKLCW KNCSGKTEQK EAEGAEWLHF ASCGEDHTVK IHRVNKCA
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 72%.
ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: elongation protein 2 homolog; Elongator complex protein 2; elongator protein 2; ELP2; SHINC-2; signal transducer and activator of transcription 3 interacting protein 1; STAT3-interacting protein 1; StIP1
Gene Aliases: ELP2; SHINC-2; STATIP1; StIP
UniProt ID: (Human) Q6IA86
Entrez Gene ID: (Human) 55250
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