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FIGURE: 1 / 1
ELP2 Antibody (PA5-90765) in WB
Western blot analysis of ELP2 in extracts of various cell lines. Samples were incubated with ELP2 Polyclonal antibody (Product # PA5-90765) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-90765
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human ELP2 (NP_0012298081)
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806229
Product Specific Information
Immunogen sequence: QNTVNPREWT PEIVISGHFD GVQDLVWDPE GEFIITVGTD QTTRLFAPWK RKDQSQVTWH EIARPQIHGY DLKCLAMINR FQFVSGADEK VLRVFSAPRN FVENFCAITG QSLNHVLCNQ DSDLPEGATV PALGLSNKAV FQGDIASQPS DEEELLTSTG FEYQQVAFQP SILTEPPTED HLLQNTLWPE VQKLYGHGYE IFCVTCNSSK TLLASACKAA KKEHAAIILW NTTSWKQVQN LVFHSLTVTQ MAFSPNEKFL LAVSRDRTWS LWKKQDTISP EFEPVFSLFA FTNKITSVHS R; Positive Samples: Mouse brain, Mouse heart, Mouse kidney, Rat spleen; Cellular Location: Cytoplasm, Nucleus
Target Information
ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: elongation protein 2 homolog; Elongator complex protein 2; ELP2; SHINC-2; signal transducer and activator of transcription 3 interacting protein 1; signal transducer and activator of transcription interacting protein 1; STAT3-interacting protein 1; StIP1
Gene Aliases: AU023723; Elp2; Epl2; Statip1; StIP1
UniProt ID: (Mouse) Q91WG4, (Rat) Q496Z0
Entrez Gene ID: (Mouse) 58523, (Rat) 307545
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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