Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
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Protein Aliases: EC 22.214.171.124; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; Protein lysine acetyltransferase ELP3; tRNA uridine(34) acetyltransferase
Gene Aliases: 2610507P14Rik; ELP3; KAT9
Molecular Function: histone modifying enzyme