Recommended positive controls: NT2D1, IMR32.
Predicted reactivity: Mouse (96%), Zebrafish (92%), Drosophila (88%), Yeast (84%), Xenopus laevis (92%), Chicken (91%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
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Protein Aliases: EC 188.8.131.52; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; Protein lysine acetyltransferase ELP3; tRNA uridine(34) acetyltransferase
Gene Aliases: ELP3; KAT9
UniProt ID: (Human) Q9H9T3
Entrez Gene ID: (Human) 55140
Molecular Function: histone modifying enzyme