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Product Details
PA5-29319
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 21 and 299 of Human ELP3
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546795
Product Specific Information
Recommended positive controls: 293T, Raji.
Predicted reactivity: Mouse (94%), Zebrafish (94%), Drosophila (90%), Yeast (80%), Xenopus laevis (91%), Chicken (94%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.3.1.48; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; tRNA uridine(34) acetyltransferase
Gene Aliases: ELP3; KAT9
UniProt ID: (Human) Q9H9T3
Entrez Gene ID: (Human) 55140
neuron migration
tRNA wobble uridine modification
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
central nervous system development
positive regulation of cell migration
histone H3 acetylation
histone H4 acetylation
regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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