Immunogen sequence: ELWKSGRYKS YSPSDLVELV ARILALVPPW TRVYRVQRDI PMPLVSSGVE HGNLRELALA RMKDLGIQCR DVRTREVGIQ EIHHKVRPYQ VELVRR
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 22.214.171.124; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; Protein lysine acetyltransferase ELP3; rCG52086-like; tRNA uridine(34) acetyltransferase
Gene Aliases: 2610507P14Rik; ELP3; KAT9
Molecular Function: histone modifying enzyme