This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
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Protein Aliases: elongation protein 4 homolog; Elongator complex protein 4; hELP4; PAX6 neighbor gene protein
Gene Aliases: A330107A17Rik; AN; C11orf19; dJ68P15A.1; ELP4; hELP4; PAX6NEB; PAXNEB