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Proteintech
EME1 Polyclonal Antibody
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Product Details
12975-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EME1 Fusion Protein Ag3580 (234-584 aa encoded by BC016470)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AALVTRMKA QRPEECLKHI IVVLDPVLLQ MEGGGQLLGA LQTMECRCVI EAQAVPCSVT WRRRAGPSED REDWVEEPTV LVLLRAEAFV SMIDNGKQGS LDSTMKGKET LQGFVTDITA KTAGKALSLV IVDQEKCFSL ELLFFDFLPC TSAQNPPRRG KQGANKQTKK QQQRQPEASI GSMVSRVDAE EALVDLQLHT EAQAQIVQSW KELADFTCAF TKAVAEAPFK KLRDETTFSF CLESDWAGGV KVDLAGRGLA LVWRRQIQQL NRVSLEMASA VVNAYPSPQL LVQAYQQCFS DKERQNLLAD IQVRRGEGVT STSRRIGPEL SRRIYLQMTT LQPHLSLDSA D (234-584 aa encoded by BC016470)
Target Information
EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Crossover junction endonuclease EME1; essential meiotic endonuclease 1 homolog 1; essential meiotic endonuclease 1 homolog 2; Essential meiotic structure-specific endonuclease 1; hMMS4; homolog of yeast EME1 endonuclease; MMS4 homolog; Msm4; SLX2 structure-specific endonuclease subunit homolog A; Structure-specific endonuclease subunit EME1; unnamed protein product
Gene Aliases: 6820428D13; EME1; MMS4; MMS4L; SLX2A
UniProt ID: (Human) Q96AY2, (Mouse) Q8BJW7
Entrez Gene ID: (Human) 146956, (Mouse) 268465, (Rat) 287634
DNA repair
DNA recombination
cellular response to DNA damage stimulus
response to intra-S DNA damage checkpoint signaling
resolution of meiotic recombination intermediates
telomere maintenance
double-strand break repair
replication fork processing
intra-S DNA damage checkpoint
resolution of mitotic recombination intermediates
nucleic acid phosphodiester bond hydrolysis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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