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          • Primary Antibodies ›
          • EMP Antibodies

          Invitrogen

          EMP Polyclonal Antibody

          View all (5) EMP antibodies

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          Cite EMP Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          EMP Antibody in Western Blot (WB)
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          EMP Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          EMP Antibody (PA5-101191) in WB

          Western blot analysis of EMP in extracts from COLO205 cells,. Samples were incubated with EMP polyclonal antibody (Product # PA5-101191). The lane on the left was treated with blocking peptide. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          EMP Antibody in Western Blot (WB)
          EMP Polyclonal Antibody

          Product Details

          PA5-101191

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human MAEA(Accession Q7L5Y9), corresponding to amino acid residues S187-R237.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2850633

          Product Specific Information

          Antibody detects endogenous levels of total MAEA.

          Target Information

          This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cell proliferation-inducing gene 5 protein; E3 ubiquitin-protein transferase MAEA; Erythroblast macrophage protein; GID complex subunit 9, FYV10 homolog; HLC-10; Human lung cancer oncogene 10 protein; lung cancer-related protein 10; Macrophage erythroblast attacher; P44EMLP

          View more View less

          Gene Aliases: 1110030D19Rik; EMLP; EMP; GID9; HLC-10; HLC10; MAEA; PIG5

          View more View less

          UniProt ID: (Human) Q7L5Y9, (Rat) Q5RKJ1, (Mouse) Q4VC33

          View more View less

          Entrez Gene ID: (Human) 10296, (Rat) 298982, (Mouse) 59003

          View more View less

          Function(s)
          actin binding
          Process(es)
          cytoskeleton organization cell adhesion negative regulation of myeloid cell apoptotic process erythrocyte maturation erythrocyte development enucleate erythrocyte development cell division cell cycle regulation of mitotic cell cycle
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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