This Antibody was verified by KnockOut to ensure that the antibody binds to the antigen stated. View Details
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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Protein Aliases: Cell proliferation-inducing gene 5 protein; E3 ubiquitin-protein transferase MAEA; EMLP; EMP; Erythroblast macrophage protein; GID complex subunit 9, FYV10 homolog; HLC-10; Human lung cancer oncogene 10 protein; lung cancer-related protein 10; Macrophage erythroblast attacher; P44EMLP; PIG5; proliferation-inducing gene 5
Gene Aliases: 1110030D19Rik; EMLP; EMP; GID9; HLC-10; HLC10; MAEA; PIG5