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Product Details
PA5-53220
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EMP2. Recombinant protein control fragment (Product #RP-91201).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2641027
Product Specific Information
Immunogen sequence: DNAWWVGDEF FADVWRICTN NTNCTVINDS FQEYST
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 68%.
Target Information
Epithelial membrane protein-2 (EMP2) is a member of the four transmembrane superfamily (TM4SF) and is thought to mediate trafficking of diverse proteins such as alpha6beta1 integrin and MHC class I to lipid raft microdomains. EMP2 has also recently been recognized as a putative tumor suppressor gene in certain model systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EMP-2; Epithelial membrane protein 2; MGC9056; Protein XMP
Gene Aliases: EMP2; XMP
UniProt ID: (Human) P54851
Entrez Gene ID: (Human) 2013
membrane raft assembly
T cell mediated cytotoxicity
positive regulation of cell-matrix adhesion
regulation of glomerular filtration
actin filament organization
cell adhesion
cell-matrix adhesion
embryo implantation
cell death
cell proliferation
positive regulation of cell proliferation
regulation of endothelial cell migration
cell migration
bleb assembly
activation of protein kinase activity
protein localization to cell surface
blood vessel endothelial cell migration
regulation of kinase activity
early endosome to late endosome transport
regulation of angiogenesis
actin-mediated cell contraction
caveola assembly
protein localization to plasma membrane
positive regulation of integrin-mediated signaling pathway
regulation of vasculogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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