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ENO1+ENO2+ENO3 Polyclonal Antibody
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Product Details
BS-6273R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ENO1+ENO2+ENO3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydrolase gamma isoform; 2-phospho-D-glycerate hydrolyase; alpha enolase (EC 4.2.1.11); alpha enolase like 1; c-Myc promoter binding protein; ENO1 intronic transcript 1; ENO1 intronic transcript 1 (non-protein coding); ENO2; Eno3; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase 2 (gamma, neuronal); enolase 2, gamma, neuronal; enolase 3 (beta, muscle); enolase 3, beta, muscle; enolase-alpha; epididymis secretory protein Li 17; epididymis secretory protein Li 279; gamma enolase; gamma-enolase-like; muscle enriched enolase; Muscle specific enolase (beta beta enolose) (two splicing products); muscle-specific enolase; muscle-specific enolase beta subunit (EC 4.2.1.11); MYC promoter-binding protein 1; neural enolase; neuron specific gamma enolase; neuron-specific enolase; neuronal enriched enolase; neurone-specific enolase; non-neural enolase; phosphopyruvate hydratase; plasminogen-binding protein; skeletal muscle enolase; tau-crystallin; transcription factor; unnamed protein product
Gene Aliases: BBE; D6Ertd375e; Eno-1; Eno-2; Eno-3; ENO1-IT1; ENO1L1; GSD13; HEL-S-17; HEL-S-279; MBP-1; MPB1; MSE; NNE; NSE; PPH; RNEN3
UniProt ID: (Human) P06733, (Human) P09104, (Human) P13929, (Mouse) P17182, (Rat) P04764, (Mouse) P17183, (Rat) P07323, (Rat) P15429, (Mouse) P21550
Entrez Gene ID: (Human) 2023, (Human) 2026, (Human) 2027, (Mouse) 13806, (Rat) 24333, (Mouse) 13807, (Rat) 24334, (Rat) 25438, (Mouse) 13808
magnesium ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcription corepressor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription corepressor activity
RNA binding
phosphopyruvate hydratase activity
protein binding
protein homodimerization activity
cadherin binding
GTPase binding
enzyme binding
identical protein binding
macromolecular complex binding
heat shock protein binding
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
gluconeogenesis
glycolytic process
positive regulation of plasminogen activation
negative regulation of cell growth
negative regulation of transcription, DNA-templated
positive regulation of muscle contraction
glyceraldehyde-3-phosphate biosynthetic process
canonical glycolysis
cellular response to interleukin-7
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
positive regulation of ATP biosynthetic process
response to xenobiotic stimulus
response to estradiol
skeletal muscle tissue regeneration
response to virus
ERK1 and ERK2 cascade
cellular response to hypoxia
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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