PA5-31476 targets ENOSF1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31476 immunogen is recombinant fragment corresponding to a region within amino acids 13 and 349 of Human ENOSF1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Another transcript variant (named rTSalpha) does not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins.
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Protein Aliases: Antisense RNA to thymidylate synthase; HSRTSBETA; L-fuconate dehydratase; Mitochondrial enolase superfamily member 1; rTS; rTS alpha; rTS beta; TYMSAS
Gene Aliases: ENOSF1; RTS; TYMSAS
UniProt ID: (Human) Q7L5Y1
Entrez Gene ID: (Human) 55556