Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 10 publications 10 publications |
Immunohistochemistry (IHC) |
- | View 9 publications 9 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ENT1 Fusion Protein Ag1881 (150-456 aa encoded by BC008954) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.16 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: INSFGAILQ GSLFGLAGLL PASYTAPIMS GQGLAGFFAS VAMICAIASG SELSESAFGY FITACAVIIL TIICYLGLPR LEFYRYYQQL KLEGPGEQET KLDLISKGEE PRAGKEESGV SVSNSQPTNE SHSIKAILKN ISVLAFSVCF IFTITIGMFP AVTVEVKSSI AGSSTWERYF IPVSCFLTFN IFDWLGRSLT AVFMWPGKDS RWLPSLVLAR LVFVPLLLLC NIKPRRYLTV VFEHDAWFIF FMAAFAFSNG YLASLCMCFG PKKVKPAEAE TAGAIMAFFL CLGLALGAVF SFLFRAIV (150-456 aa encoded by BC008954)
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative transporter that is sensitive to inhibition by nitrobenzylthioinosine. Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Equilibrative NBMPR-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative nucleoside transporter 1; equilibrative nucleoside transporter 1 variant delta 11; HENT1; NBMPR-sensitive equilibrative nucleoside transporter; Nucleoside transporter, es-type; solute carrier family 29 (equilibrative nucleoside transporter), member 1; solute carrier family 29 (nucleoside transporters), member 1; Solute carrier family 29 member 1; solute carrier family 29, member 1
Gene Aliases: 1200014D21Rik; AA407560; ENT1; rENT1; SLC29A1
UniProt ID: (Human) Q99808, (Mouse) Q9JIM1, (Rat) O54698
Entrez Gene ID: (Human) 2030, (Mouse) 63959, (Rat) 63997
Molecular Function:
transporter
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