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Invitrogen
ENT1 Polyclonal Antibody
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Product Details
PA5-33030
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from C-terminus of human ENT1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit (100%).
Target Information
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative transporter that is sensitive to inhibition by nitrobenzylthioinosine. Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cENT1; ENT1; Equilibrative NBMPR-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative nucleoside transporter 1; equilibrative nucleoside transporter 1 variant delta 11; es nucleoside transporter; HENT1; inhibitor-sensitive equilibrative nucleoside transporter 1; mENT1; NBMPR-sensitive equilibrative nucleoside transporter; Nucleoside transporter, es-type; rENT1; solute carrier family 29 (equilibrative nucleoside transporter), member 1; solute carrier family 29 (nucleoside transporters), member 1; Solute carrier family 29 member 1; solute carrier family 29 member 1 (Augustine blood group); solute carrier family 29, member 1; unnamed protein product
Gene Aliases: 1200014D21Rik; AA407560; AUG; ENT1; hENT1; rENT1; SLC29A1
UniProt ID: (Human) Q99808, (Mouse) Q9JIM1, (Rat) O54698
Entrez Gene ID: (Rabbit) 100357908, (Dog) 442966, (Human) 2030, (Horse) 100055498, (Bovine) 510932, (Mouse) 63959, (Rat) 63997
neurotransmitter transporter activity
nucleoside transmembrane transporter activity
adenine transmembrane transporter activity
guanine transmembrane transporter activity
uracil transmembrane transporter activity
purine nucleoside transmembrane transporter activity
cytidine transmembrane transporter activity
uridine transmembrane transporter activity
pyrimidine- and adenine-specific:sodium symporter activity
transporter
neurotransmitter uptake
nucleobase-containing compound metabolic process
xenobiotic metabolic process
neurotransmitter transport
drug transmembrane transport
lactation
nucleobase transport
adenine transport
nucleoside transport
purine nucleoside transmembrane transport
cytidine transport
uridine transport
adenosine transport
inosine transport
hypoxanthine transport
thymine transport
excitatory postsynaptic potential
cellular response to glucose stimulus
cellular response to hypoxia
pyrimidine-containing compound transmembrane transport
transport across blood-brain barrier
nucleoside transmembrane transport
guanine transmembrane transport
uracil transmembrane transport
pyrimidine nucleobase transmembrane transport
purine nucleobase transmembrane transport
transport
sleep
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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