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Invitrogen
ENT2 Polyclonal Antibody
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Product Details
PA5-53746
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC29A2. Recombinant protein control fragment (Product #RP-91298).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KFARYYLANK SSQAQAQELE TKAELLQSDE NGIPSSPQKV ALTLDLDLEK EPESEPDEPQ KPGKPSVFTV FQK
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 70%.
Target Information
SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis. SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium. As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 36 kDa nucleolar protein HNP36; Delayed-early response protein 12; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; hENT2; Hydrophobic nucleolar protein, 36 kDa; hydrophobic nucleolar protein, 36kD; Nucleoside transporter, ei-type; solute carrier family 29 (equilibrative nucleoside transporter), member 2; solute carrier family 29 (nucleoside transporters), member 2; Solute carrier family 29 member 2; unnamed protein product
Gene Aliases: DER12; ENT2; hENT2; HNP36; SLC29A2
UniProt ID: (Human) Q14542
Entrez Gene ID: (Human) 3177
neurotransmitter transporter activity
nucleoside transmembrane transporter activity
nucleobase transmembrane transporter activity
adenine transmembrane transporter activity
guanine transmembrane transporter activity
uracil transmembrane transporter activity
purine nucleoside transmembrane transporter activity
cytidine transmembrane transporter activity
uridine transmembrane transporter activity
neurotransmitter uptake
neurotransmitter transport
drug transmembrane transport
nucleobase transport
adenine transport
guanine transport
nucleoside transport
purine nucleoside transmembrane transport
cytidine transport
uridine transport
adenosine transport
inosine transport
hypoxanthine transport
thymine transport
pyrimidine-containing compound transmembrane transport
transport across blood-brain barrier
nucleoside transmembrane transport
guanine transmembrane transport
uracil transmembrane transport
purine nucleobase transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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