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Proteintech
EPB41 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
13014-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPB41 Fusion Protein Ag4075 (1-299 aa encoded by BC039079)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.69 mg/mL
Amount
103.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTTEKSLVT EAENSQHQQK EEGEEAINSG QQEPQQEESC QTAAEGDNWC EQKLKASNGD TPTHEDLTKN KERTSESRGL SRLFSSFLKR PKSQVSEEEG KEVESDKEKG EGGQKEIEFG TSLDEEIILK APIAAPEPEL KTDPSLDLHS LSSAETQPAQ EELREDPDFE IKEGEGLEEC SKIEVKEESP QSKAETELKA SQKPIRKHRN MHCKVSLLDD TVYECVVEKH AKGQDLLKRV CEHLNLLEED YFGLAIWDNA TSKTWLDSAK EIKKQVRGVP WNFTFNVKFY PPDPAQLTED (1-299 aa encoded by BC039079)
Target Information
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 4.1 protein; band 4.1; elliptocytosis 1, RH-linked; EPB4.1; erythrocyte protein band 4.1; erythrocyte surface protein band 4.1; erythroid protein 4.1 isoform A; erythroid protein 4.1 isoform B; P4.1; Protein 4.1R; unnamed protein product
Gene Aliases: 4.1R; D4Ertd442e; EL1; Elp-1; Elp1; Epb4.1; HE; mKIAA4056; RGD1564762
UniProt ID: (Human) P11171, (Mouse) P48193
Entrez Gene ID: (Human) 2035, (Rat) 313052, (Mouse) 269587
cortical actin cytoskeleton organization
actomyosin structure organization
regulation of calcium ion transport
protein-containing complex assembly
regulation of intestinal absorption
positive regulation of protein localization to cell cortex
regulation of cell shape
actin cytoskeleton organization
response to fluid shear stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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