|Tested species reactivity||Human, Mouse, Non-human primate, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to internal residues 400-500 of the human protein. [Swiss-Prot# Q9Y2J2]|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This EPB41L3 antibody is useful for Western blot, where bands are seen at ~120 and 96 kDa.
It detects both isoforms A and B in mouse brain lysates.
It detects human isoform A strongly and isoform B more weakly.Suggested positive control: human and mouse brain lysate, HeLa whole cell lysate, Hela whole cell lysate, mouse brain lysate, human brain lysate.
Protein 4.1B is a member of a family of similar proteins whose expression is frequently lost in a variety of human tumors, including meningiomas, non-small-cell lung cancers, and breast carcinomas and is frequently down-regulated in human clinical prostate cancer. Studies have shown that Protein 4.1B normally triggers death in metastatic cells, thereby preventing cancer from spreading. A clinical test for Protein 4.1B activity could be useful in assessing the metastatic potential of prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.