Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: LDTSTIHGD WGWLTYPAHG WDSINEVDES FQPIHTYQVC NVMSPNQNNW LRTSWVPRDG ARRVYAEIKF TLRDCNSMPG VLGTCKETFN LYYLESDRDL GASTQESQFL KIDTIAADES FTGADLGVRR LKLNTEVRSV GPLSKRGFYL AFQDIGACLA ILSLRIYYKK CPAMVRNLAA FSEAVTGADS SSLVEVRGQC VRHSEERDTP KMYCSAEGEW LVPIGKCVCS AGYEERRDAC VACELGFYKS APGDQLCARC PPHSHSAAPA AQACHCDLSY YRAALDPPSS ACTRPPSAPV NLISSVNGTS VTLEWAP (35-350 aa encoded by BC038796)
EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); hydroxyaryl-protein kinase; protein-tyrosine kinase; Tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
Gene Aliases: AW047546; EEK; EK3; EPHA8; HEK3; KIAA1459; mKIAA1459
UniProt ID: (Human) P29322, (Mouse) O09127
Entrez Gene ID: (Human) 2046, (Rat) 60589, (Mouse) 13842
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