Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-120662
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human EPHX2 (NP_0019702)
Conjugate
Form
Liquid
Concentration
2.74 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914234
Product Specific Information
Positive test controls include: 293T, LO2, SW480, Mouse liver, Mouse kidney, Mouse heart, Rat kidney. The target is usually found in the following locations: Cytoplasm, Peroxisome.^M
^M
Immunogen sequence: LALPRGLLND AFQKGGPEGA TTRLMKGEIT LSQWIPLMEE NCRKCSETAK VCLPKNFSIK EIFDKAISAR KINRPMLQAA LMLRKKGFTT AILTNTWLDD RAERDGLAQL MCELKMHFDF LIESCQVGMV KPEPQIYKFL LDTLKASPSE VVFLDDIGAN LKPARDLGMV TILVQDTDTA LKELEKVTGI QLLNTPAPLP TSCNPSDMSH G
Target Information
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Bifunctional epoxide hydrolase 2; CEH; cytosolic epoxide hydrolase; epoxide hydratase; epoxide hydrolase 2, cytoplasmic; epoxide hydrolase 2, cytosolic; epoxide hydrolase 2C; epoxide hydrolase, soluble; SEH; soluble epoxide hydrolase
Gene Aliases: CEH; Eph2; EPHX2; SEH; sEP
UniProt ID: (Human) P34913, (Mouse) P34914, (Rat) P80299
Entrez Gene ID: (Human) 2053, (Mouse) 13850, (Rat) 65030
xenobiotic metabolic process
cellular calcium ion homeostasis
inflammatory response
regulation of blood pressure
response to toxic substance
positive regulation of gene expression
dephosphorylation
drug metabolic process
epoxygenase P450 pathway
cholesterol homeostasis
positive regulation of vasodilation
stilbene catabolic process
phospholipid dephosphorylation
reactive oxygen species metabolic process
regulation of cholesterol metabolic process
prostaglandin production involved in inflammatory response
lipid metabolic process
metabolic process
sensory perception of pain
aromatic compound catabolic process
linoleic acid metabolic process
positive regulation of blood pressure
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support