Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Orangutan (95%) Gibbon, Monkey (89%) Marmoset (84%).
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
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Protein Aliases: Bifunctional epoxide hydrolase 2; CEH; Cytosolic epoxide hydrolase 2; Epoxide hydratase; epoxide hydrolase 2, cytoplasmic; epoxide hydrolase 2, cytosolic; epoxide hydrolase, soluble; Lipid-phosphate phosphatase; SEH; Soluble epoxide hydrolase
Gene Aliases: CEH; EPHX2; SEH
UniProt ID: (Human) P34913
Entrez Gene ID: (Human) 2053
Molecular Function: hydrolase