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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
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Protein Aliases: epidermal growth factor receptor pathway substrate 15-related sequence; epidermal growth factor receptor substrate EPS15R; eps15-related protein; involved in signaling by the epidermal growth factor receptor; Method: conceptual translation supplied by author.; unnamed protein product
Gene Aliases: 9830147J04Rik; Eps15-rs; EPS15R
UniProt ID: (Human) Q9UBC2, (Mouse) Q60902
Entrez Gene ID: (Human) 58513, (Mouse) 13859, (Rat) 361120
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