This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain, rat brain.
Predicted reactivity: Mouse (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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Protein Aliases: Epidermal growth factor receptor kinase substrate 8; epidermal growth factor receptor pathway substrate 8
Gene Aliases: AW261790; DFNB102; EPS8
Molecular Function: transmembrane receptor regulatory/adaptor protein