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Abnova
EPS8L1 Polyclonal Antibody, MaxPab™
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Product Details
H00054869-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPS8L1 (NP_631943.1, 1 a.a. approximately 551 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGRKAIVLAI ANTSLAFPLC QHLVTFCLGE DDGVHTVEDA SRKLAVMDSQ GRVWAQEMLL RVSPDHVTLL DPASKEELES YPLGAIVRCD AVMPPGRSRS LLLLVCQEPE RAQPDVHFFQ GLRLGAELIR EDIQGALHNY RSGRGERRAA ALRATQEELQ RDRSPAAETP PLQRRPSVRA VISTVERGAG RGRPQAKPIP EAEEAQRPEP VGTSSNADSA SPDLGPRGPD LAVLQAEREV DILNHVFDDV ESFVSRLQKS AEAARVLEHR ERGRRSRRRA AGEGLLTLRA KPPSEAEYTD VLQKIKYAFS LLARLRGNIA DPSSPELLHF LFGPLQMIVN TSGGPEFASS VRRPHLTSDA VALLRDNVTP RENELWTSLG DSWTRPGLEL SPEEGPPYRP EFFSGWEPPV TDPQSRAWED PVEKQLQHER RRRQVTQATQ QGRGWEVRGR GRSAWPRLTR LSYFLQQSAP QVAVNGHRDL EPESEPQLES ETAGKWVLCN YDFQARNSSE LSVKQRDVLE VLEDKEKVSE LEAVMEKQKK KVEGEVEMEV I
Target Information
Eps8L1 (EPS8-like 1), also known as DRC3 or EPS8R1, is a 723 amino acid protein that localizes to the cytoplasm and belongs to the Eps8 (epidermal growth factor receptor pathway substrate 8) family. Expressed in placental tissue, Eps8L1 functions to stimulate the guanine exchange activity of Sos 1 (son of sevenless homolog 1), a protein that promotes the exchange of Ras-bound GDP for GTP. Additionally, Eps8L1 is thought to associate with Actin and, via this association, may play a role in membrane ruffling and remodeling of the Actin cytoskeleton. Through its ability to regulate protein activation and cytoskeleton dynamics, Eps8L1 may participate in cell growth and differentiation events within the cell. Eps8L1 contains one SH3 domain and is expressed as four isoforms due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: down-regulated in esophageal cancer cDNA 3; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8 like 1; EPS8-like protein 1; EPS8-related protein 1; tumor-associated protein; unnamed protein product
Gene Aliases: DRC3; EPS8L1; EPS8R1; PP10566
UniProt ID: (Human) Q8TE68
Entrez Gene ID: (Human) 54869
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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