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AbboMax
ER81 Polyclonal Antibody
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FIGURE: 1 / 2
ER81 Antibody (602-930) in IHC (P)
Immunohistochemistry: Lung tissue (FFPE) stained with Rabbit anti-ER81 (Cat# 602-930) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Product Details
602-930
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the C-terminus of human ER81 protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Mouse brain
Cellular location: Nuclear, Cytoplasmic.
Target Information
ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781L0674; ets related protein 81; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; MGC104699; MGC120533; MGC120534
Gene Aliases: ER81; Etsrp81; ETV1
UniProt ID: (Human) P50549, (Mouse) P41164
Entrez Gene ID: (Human) 2115, (Rat) 362733, (Mouse) 14009
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
transcription from RNA polymerase II promoter
axon guidance
muscle organ development
mechanosensory behavior
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
regulation of transcription from RNA polymerase II promoter
cell differentiation
positive regulation of transcription, DNA-templated
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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