Recommended positive controls: A431, ERF-transfected 293T.
Predicted reactivity: Mouse (99%), Rat (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).
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Protein Aliases: Est2 repressor factor; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE-2
Gene Aliases: CRS4; ERF; PE-2; PE2
Molecular Function: winged helix/forkhead transcription factor