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Proteintech
ERLIN1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
17311-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ERLIN1 Fusion Protein Ag11279 (29-346 aa encoded by BC031791)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GHLAVYYRG GALLTSPSGP GYHIMLPFIT TFRSVQTTLQ TDEVKNVPCG TSGGVMIYID RIEVVNMLAP YAVFDIVRNY TADYDKTLIF NKIHHELNQF CSAHTLQEVY IELFDQIDEN LKQALQKDLN LMAPGLTIQA VRVTKPKIPE AIRRNFELME AEKTKLLIAA QKQKVVEKEA ETERKKAVIE AEKIAQVAKI RFQQKVMEKE TEKRISEIED AAFLAREKAK ADAEYYAAHK YATSNKHKLT PEYLELKKYQ AIASNSKIYF GSNIPNMFVD SSCALKYSDI RTGRESSLPS KEALEPSGEN VIQNKESTG (29-346 aa encoded by BC031791)
Target Information
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; endoplasmic reticulum lipid raft-associated protein 1; OTTHUMP00000059425; OTTHUMP00000197867; protein KE04 homolog; SPFH domain family, member 1; SPFH domain-containing protein 1; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; unnamed protein product
Gene Aliases: 2810439N09Rik; C10orf69; Erlin-1; KE04; KEO4; RGD1307058; SPFH1; SPG62
UniProt ID: (Human) O75477, (Mouse) Q91X78
Entrez Gene ID: (Human) 10613, (Rat) 293939, (Mouse) 226144
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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