Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: WCRFSQMLHP IFEEASDVIK EEFPNENQVV FARVDCDQHS DIAQRYRISK YPTLKLFRNG MMMKREYRGQ RSVKALADYI RQQKSDPIQE IRDLAEITTL DRSKRNIIGY FEQKDSDNYR VFERVANILH DDCAFLSAFG DVSKPERYSG DNIIYKPPGH SAPDMVYLGA MTNFDVTYNW IQDKCVPLVR EITFENGEEL TEEGLPFLIL FHMKEDTESL EIFQNEVARQ LISEKGTINF LHADCDKFRH PLLHIQKTPA DCPVIAIDSF RHMYVFGDFK DVLIPGKLKQ FVFDLHSGKL HREFHHGPDP TDTAPGEQAQ DVASSPPESS FQKLAPSEYR YTLLRDRDEL
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; endoplasmic reticulum resident protein 44kDa; endoplasmic reticulum resident protein ERp44; ER protein 44; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4
Gene Aliases: 1110001E24Rik; AI849526; AL033348; BWK4; ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26, (Mouse) Q9D1Q6
Entrez Gene ID: (Human) 23071, (Mouse) 76299, (Rat) 298066
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