Keep as concentrated solution.
Positive Control: HepG2, HCT116, 293T, A431, HeLa, Neuro2A, GL261, C8D30, PC-12, Rat2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa glucose-regulated protein antibody; 58 kDa microsomal protein; 58 kDa microsomal protein antibody; 58kDa antibody; Disulfide isomerase ER-60; disulfide isomerase ER-60 antibody; endoplasmic reticulum P58; endoplasmic reticulum P58 antibody; endoplasmic reticulum protein; Endoplasmic reticulum resident protein 57; endoplasmic reticulum resident protein 57 antibody; Endoplasmic reticulum resident protein 60; endoplasmic reticulum resident protein 60 antibody; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER protein 57; ER protein 57 antibody; ER protein 60; ER protein 60 antibody; ER-60 protease; ER60 antibody; ERp57 antibody; ERp60; ERp60 antibody; ERp61 antibody; glucose regulated protein; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP57 antibody; GRP58 antibody; HIP-70; HsT17083 antibody; member 3 antibody; oxidoreductase ERp57; p58; P58 antibody; PDIA3 antibody; phospholipase C, alpha; phospholipase C-alpha; phospholipase C-alpha antibody; PI-PLC antibody; protein disulfide isomerase associated 3; protein disulfide isomerase family A; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide isomerase-associated 3 antibody; Protein disulfide-isomerase A3; protein disulfide-isomerase A3 antibody; Q-2
Gene Aliases: 58kDa; ER60; Erp; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDI; PDI-Q2; PDIA3; PI-PLC; PLC[a]; Plca