PA1-315 detects ERR2 from mouse and rat kidney extracts.
PA1-315 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects an ~48 kDa protein representing ERR2 from rat kidney extract.
The PA1-315 immunogen is a synthetic peptide corresponding to residues D(376) Y E L S Q R H E E P R R(388) of mouse ERR2. This peptide (Cat. # PEP-251) is available for use in neutralization and control experiments.
Estrogen-related receptor 2 (ERR beta, ERR2) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. It has been shown the ERR2 plays a critical functional role in placental development.
The corresponding gene for the ERR2 is NR3B2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ERR-beta; estrogen receptor related 2; Estrogen receptor-like 2; Estrogen-related receptor beta; estrogen-related receptor, beta; Nuclear receptor subfamily 3 group B member 2; Steroid hormone receptor ERR2
Gene Aliases: Err-2; Err2; Errb; Esrl2; Esrrb; Estrrb; Nr3b2