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Proteintech
ESRRG Polyclonal Antibody
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Product Details
14017-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ESRRG Fusion Protein Ag5127 (94-442 aa encoded by BC064700)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human ESRRG.
Immunogen sequence: EYMLNSMPK RLCLVCGDIA SGYHYGVASC EACKAFFKRT IQGNIEYSCP ATNECEITKR RRKSCQACRF MKCLKVGMLK EGVRLDRVRG GRQKYKRRID AENSPYLNPQ LVQPAKKPLL WSDPADNKIV SHLLVAEPEK IYAMPDPTVP DSDIKALTTL CDLADRELVV IIGWAKHIPG FSTLSLADQM SLLQSAWMEI LILGVVYRSL SFEDELVYAD DYIMDEDQSK LAGLLDLNNA ILQLVKKYKS MKLEKEEFVT LKAIALANSD SMHIEDVEAV QKLQDVLHEA LQDYEAGQHM EDPRRAGKML MTLPLLRQTS TKAVQHFYNI KLEGKVPMHK LFLEMLEAKV (94-442 aa encoded by BC064700)
Target Information
Estrogen-related receptor gamma (ERRG, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. ERRG acts as a transcription activator in the absence of a bound ligand. It binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. ERRG also induces the expression of PERM1 in the skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp781L1617; ERR gamma; ERR gamma-2; ERR3; Estrogen receptor-related protein 3; estrogen-related receptor 3; Estrogen-related receptor gamma; FLJ16023; Nuclear receptor subfamily 3 group B member 3; orphan nuclear receptor; unnamed protein product
Gene Aliases: ERR-gamma; ERR3; ERRg; ERRG2; ERRgamma; ESRRG; KIAA0832; mKIAA0832; NR3B3
UniProt ID: (Human) P62508, (Mouse) P62509, (Rat) P62510
Entrez Gene ID: (Human) 2104, (Mouse) 26381, (Rat) 360896
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
steroid binding
protein binding
zinc ion binding
estrogen response element binding
identical protein binding
sequence-specific DNA binding
metal ion binding
AF-2 domain binding
sequence-specific double-stranded DNA binding
retinoic acid receptor activity
calmodulin binding
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
intracellular steroid hormone receptor signaling pathway
positive regulation of cold-induced thermogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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