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Invitrogen
ESRRG Polyclonal Antibody
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Product Details
PA5-115201
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ESRRG(Accession P62508), corresponding to amino acid residues R29-L79.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ESRRG.
Target Information
Estrogen-related receptor gamma (ERRG, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. ERRG acts as a transcription activator in the absence of a bound ligand. It binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. ERRG also induces the expression of PERM1 in the skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781L1617; ERR gamma; ERR gamma-2; Estrogen receptor-related protein 3; estrogen-related receptor 3; Estrogen-related receptor gamma; FLJ16023; Nuclear receptor subfamily 3 group B member 3
Gene Aliases: ERR3; Errg; ERRG2; ERRgamma; ESRRG; KIAA0832; mKIAA0832; NR3B3
UniProt ID: (Human) P62508, (Mouse) P62509, (Rat) P62510
Entrez Gene ID: (Human) 2104, (Mouse) 26381, (Rat) 360896
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
steroid hormone receptor activity
retinoic acid receptor activity
steroid binding
protein binding
zinc ion binding
AF-2 domain binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
calmodulin binding
sequence-specific DNA binding
metal ion binding
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
transcription initiation from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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