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Proteintech
ETFDH Polyclonal Antibody
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Product Details
11109-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ETFDH Fusion Protein Ag1568 (269-617 aa encoded by BC011890)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to ETFDH.
Immunogen sequence: QTYGIGLKE LWVIDEKNWK PGRVDHTVGW PLDRHTYGGS FLYHLNEGEP LVALGLVVGL DYQNPYLSPF REFQRWKHHP SIRPTLEGGK RIAYGARALN EGGFQSIPKL TFPGGLLIGC SPGFMNVPKI KGTHTAMKSG ILAAESIFNQ LTSENLQSKT IGLHVTEYED NLKNSWVWKE LYSVRNIRPS CHGVLGVYGG MIYTGIFYWI LRGMEPWTLK HKGSDFERLK PAKDCTPIEY PKPDGQISFD LLSSVALSGT NHEHDQPAHL TLRDDSIPVN RNLSIYDGPE QRFCPAGVYE FVPVEQGDGF RLQINAQNCV HCKTCDIKDP SQNINWVVPE GGGGPAYNGM (269-617 aa encoded by BC011890)
Target Information
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase
Gene Aliases: 0610010I20Rik; AV001013; ETFDH; ETFQO; MADD
UniProt ID: (Human) Q16134, (Mouse) Q921G7
Entrez Gene ID: (Human) 2110, (Rat) 295143, (Mouse) 66841
electron-transferring-flavoprotein dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, oxidizing metal ions with flavin as acceptor
metal ion binding
quinone binding
ubiquinone binding
flavin adenine dinucleotide binding
4 iron, 4 sulfur cluster binding
iron-sulfur cluster binding
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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