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Proteintech
ETS2 Polyclonal Antibody
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Product Details
12280-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ETS2 Fusion Protein Ag2929 (84-444 aa encoded by BC017040)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KATFSGFKK EQRRLGIPKN PWLWSEQQVC QWLLWATNEF SLVNVNLQRF GMNGQMLCNL GKERFLELAP DFVGDILWEH LEQMIKENQE KTEDQYEENS HLTSVPHWIN SNTLGFGTEQ APYGMQTQNY PKGGLLDSMC PASTPSVLSS EQEFQMFPKS RLSSVSVTYC SVSQDFPGSN LNLLTNNSGT PKDHDSPENG ADSFESSDSL LQSWNSQSSL LDVQRVPSFE SFEDDCSQSL CLNKPTMSFK DYIQERSDPV EQGKPVIPAA VLAGFTGSGP IQLWQFLLEL LSDKSCQSFI SWTGDGWEFK LADPDEVARR WGKRKNKPKM NYEKLSRGLR YYYDKNIIHK TSGKRYVYRF VC (84-444 aa encoded by BC017040)
Target Information
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: oncogene ETS-2; Protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2
Gene Aliases: AU022856; Ets-2; ETS2; ETS2IT1
UniProt ID: (Human) A6NM68, (Mouse) P15037
Entrez Gene ID: (Human) 2114, (Mouse) 23872
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
glucocorticoid receptor binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
ectodermal cell fate commitment
transcription, DNA-templated
mesoderm development
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
primitive streak formation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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