|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-27592 detects EWSR1 from human, mouse, and rat samples.
PA1-27592 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488
Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking. or interfering with the normal function of CTD-POLII within the transcription initiation complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.