Invitrogen

EXO1 Polyclonal Antibody

View all (14) EXO1 antibodies

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EXO1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of EXO1 in A-431 cells using a EXO1 polyclonal antibody (Product # PA5-84141). The analysis shows localization to nucleoplasm & nuclear bodies.

EXO1 Antibody in Western Blot (WB) — Western blot analysis of EXO1 by a EXO1 polyclonal antibody (Product # PA5-84141). Analysis in human cell line RT-4 and human cell line U-251 MG.

Product Details

PA5-84141

Applications	Tested Dilution	Publications
Western Blot (WB)	0.04-0.4 µg/mL	-
Immunocytochemistry (ICC/IF)	0.25-2 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human EXO1
Conjugate	Unconjugated
Form	Liquid
Concentration	0.3 mg/mL
Purification	Affinity Chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2791293

Product Specific Information

Immunogen sequence: LDETAVTDKE NNLHESEYGD QEGKRLVDTD VARNSSDDIP NNHIPGDHIP DKATVFTDEE SYSFKSSKFT RTISPPTLGT LRSCFSWSGG LGDFSRTPSP SPSTALQQFR RKSDSPTSLP ENNMSDVSQL K

Target Information

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Exonuclease 1; Exonuclease I; hExo1; hExoI; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1

Gene Aliases: EXO1; EXOI; HEX1; hExoI

UniProt ID: (Human) Q9UQ84

Entrez Gene ID: (Human) 9156

Molecular Function: exodeoxyribonuclease

DNA synthesis involved in DNA repair strand displacement humoral immune response mediated by circulating immunoglobulin DNA replication DNA repair mismatch repair DNA recombination somatic hypermutation of immunoglobulin genes isotype switching meiotic cell cycle RNA phosphodiester bond hydrolysis, endonucleolytic regulation of signal transduction by p53 class mediator

Process(es)

DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity