Invitrogen

EXO1 Polyclonal Antibody

View all (14) EXO1 antibodies

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EXO1 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of EXO1 in A-431 cells using a EXO1 polyclonal antibody (Product # PA5-84141). The analysis shows localization to nucleoplasm and nuclear bodies.

EXO1 Antibody in Western Blot (WB) — Western blot analysis of EXO1 by a EXO1 polyclonal antibody (Product # PA5-84141). Analysis in human cell line RT-4 and human cell line U-251 MG.

Product Details

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC)

0.25-2 µg/mL

-

Immunofluorescence (IF)

0.25-2 µg/mL

-

Western Blot (WB)

0.04-0.4 µg/mL

-

Product Specifications

Species

Human

Expression System

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EXO1

Conjugate

Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2791293

Product Specific Information

Immunogen sequence: LDETAVTDKE NNLHESEYGD QEGKRLVDTD VARNSSDDIP NNHIPGDHIP DKATVFTDEE SYSFKSSKFT RTISPPTLGT LRSCFSWSGG LGDFSRTPSP SPSTALQQFR RKSDSPTSLP ENNMSDVSQL K

Target Information

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Exonuclease 1; Exonuclease I; hExo1; hExoI; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1

Gene Aliases: EXO1; EXOI; HEX1; hExoI

UniProt ID: (Human) Q9UQ84

Entrez Gene ID: (Human) 9156

Molecular Function: DNA binding protein damaged DNA-binding protein endodeoxyribonuclease exodeoxyribonuclease hydrolase nuclease nucleic acid binding

DNA synthesis involved in DNA repair strand displacement humoral immune response mediated by circulating immunoglobulin DNA replication DNA repair mismatch repair DNA recombination somatic hypermutation of immunoglobulin genes isotype switching meiotic cell cycle RNA phosphodiester bond hydrolysis, endonucleolytic regulation of signal transduction by p53 class mediator

Process(es)

DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity