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The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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Protein Aliases: Exocyst complex component 1; Exocyst complex component Sec3; SEC3-like 1
Gene Aliases: 2810407P21Rik; A730011E05Rik; BM-012; BM-102; EXOC1; SEC3; SEC3L1; SEC3P
UniProt ID: (Human) Q9NV70, (Mouse) Q8R3S6
Entrez Gene ID: (Human) 55763, (Mouse) 69940, (Rat) 305287
Molecular Function:
transfer/carrier protein
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