Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 5 publications 5 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
- | View 4 publications 4 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
EXOC1 Fusion Protein Ag2303 (139-488 aa encoded by BC020650) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.25 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MPGTMAEAE DLDGGTLSRQ HNCGTPLPVS SEKDMIRQMM IKIFRCIEPE LNNLIALGDK IDSFNSLYML VKMSHHVWTA QNVDPASFLS TTLGNVLVTV KRNFDKCISN QIRQMEEVKI SKKSKVGILP FVAEFEEFAG LAESIFKNAE RRGDLDKAYT KLIRGVFVNV EKVANESQKT PRDVVMMENF HHIFATLSRL KISCLEAEKK EAKQKYTDHL QSYVIYSLGQ PLEKLNHFFE GVEARVAQGI REEEVSYQLA FNKQELRKVI KEYPGKEVKK GLDNLYKKVD KHLCEEENLL QVVWHSMQDE FIRQYKHFEG LIARCYPGSG VTMEFTIQDI LDYCSSIAQS H (139-488 aa encoded by BC020650)
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exocyst complex component 1; Exocyst complex component Sec3; SEC3-like 1
Gene Aliases: 2810407P21Rik; A730011E05Rik; BM-012; BM-102; EXOC1; SEC3; SEC3L1; SEC3P
UniProt ID: (Human) Q9NV70, (Mouse) Q8R3S6
Entrez Gene ID: (Human) 55763, (Mouse) 69940, (Rat) 305287
Molecular Function:
SNARE protein
membrane traffic protein
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