Proteintech

EXOC1 Polyclonal Antibody

View all (9) EXOC1 antibodies

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EXOC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human gliomas using 11690-1-AP (EXOC1 antibody) at dilution of 1:50 (under 10x lens).

EXOC1 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 11690-1-AP (EXOC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

EXOC1 Antibody in Western Blot (WB) — Human brain tissue were subjected to SDS PAGE followed by western blot with 11690-1-AP (EXOC1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

EXOC1 Antibody in Western Blot (WB) — Rat brain tissue were subjected to SDS PAGE followed by western blot with 11690-1-AP (EXOC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

EXOC1 Antibody in Immunoprecipitation (IP) — IP result of anti-EXOC1 (IP:11690-1-AP, 3ug; Detection:11690-1-AP 1:1000) with mouse brain tissue lysate 3600ug.

Product Details

11690-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 5 publications 5 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	-	View 4 publications 4 publications
Immunoprecipitation (IP)	0.5-4.0 µg	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	EXOC1 Fusion Protein Ag2303 (139-488 aa encoded by BC020650) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.25 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MPGTMAEAE DLDGGTLSRQ HNCGTPLPVS SEKDMIRQMM IKIFRCIEPE LNNLIALGDK IDSFNSLYML VKMSHHVWTA QNVDPASFLS TTLGNVLVTV KRNFDKCISN QIRQMEEVKI SKKSKVGILP FVAEFEEFAG LAESIFKNAE RRGDLDKAYT KLIRGVFVNV EKVANESQKT PRDVVMMENF HHIFATLSRL KISCLEAEKK EAKQKYTDHL QSYVIYSLGQ PLEKLNHFFE GVEARVAQGI REEEVSYQLA FNKQELRKVI KEYPGKEVKK GLDNLYKKVD KHLCEEENLL QVVWHSMQDE FIRQYKHFEG LIARCYPGSG VTMEFTIQDI LDYCSSIAQS H (139-488 aa encoded by BC020650)

Target Information

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients.

Cell cycle (Georgetown, Tex.)

Dai Y,Tang Z,Yang Z,Zhang L,Deng Q,Zhang X,Yu Y,Liu X,Zhu J

Fri Nov 08 00:00:00 EST 2019

EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients.

Cell cycle (Georgetown, Tex.)

Dai Y,Tang Z,Yang Z,Zhang L,Deng Q,Zhang X,Yu Y,Liu X,Zhu J

Fri Nov 08 00:00:00 EST 2019

A phosphoinositide conversion mechanism for exit from endosomes.

Nature

Ketel K,Krauss M,Nicot AS,Puchkov D,Wieffer M,Müller R,Subramanian D,Schultz C,Laporte J,Haucke V

Thu Jan 21 00:00:00 EST 2016

Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics.

Scientific reports

Park SJ,Jeong J,Park YU,Park KS,Lee H,Lee N,Kim SM,Kuroda K,Nguyen MD,Kaibuchi K,Park SK

Tue Mar 03 00:00:00 EST 2015

Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics.

Scientific reports

Park SJ,Jeong J,Park YU,Park KS,Lee H,Lee N,Kim SM,Kuroda K,Nguyen MD,Kaibuchi K,Park SK

Tue Mar 03 00:00:00 EST 2015

Exocyst complex protein expression in the human placenta.

Placenta

Gonzalez IM,Ackerman WE,Vandre DD,Robinson JM

Tue Jul 01 00:00:00 EDT 2014

Exocyst complex protein expression in the human placenta.

Placenta

Gonzalez IM,Ackerman WE,Vandre DD,Robinson JM

Tue Jul 01 00:00:00 EDT 2014

Syntaxin 16 is a master recruitment factor for cytokinesis.

Molecular biology of the cell

Neto H,Kaupisch A,Collins LL,Gould GW

Sun Dec 01 00:00:00 EST 2013

Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.

Retrovirology

Mukerji J,Olivieri KC,Misra V,Agopian KA,Gabuzda D

Fri Jun 22 00:00:00 EDT 2012

Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.

Retrovirology

Mukerji J,Olivieri KC,Misra V,Agopian KA,Gabuzda D

Fri Jun 22 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: Exocyst complex component 1; Exocyst complex component Sec3; SEC3-like 1

Gene Aliases: 2810407P21Rik; A730011E05Rik; BM-012; BM-102; EXOC1; SEC3; SEC3L1; SEC3P

UniProt ID: (Human) Q9NV70, (Mouse) Q8R3S6

Entrez Gene ID: (Human) 55763, (Mouse) 69940, (Rat) 305287

Molecular Function: SNARE protein membrane traffic protein

exocytosis Golgi to plasma membrane transport protein transport regulation of macroautophagy phosphatidylinositol-mediated signaling positive regulation of protein secretion exocyst localization transport

Process(es)

protein binding phosphatidylinositol-4,5-bisphosphate binding GTP-Rho binding molecular_function