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Proteintech
EXOC1 Polyclonal Antibody
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Product Details
11690-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EXOC1 Fusion Protein Ag2303 (139-488 aa encoded by BC020650)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPGTMAEAE DLDGGTLSRQ HNCGTPLPVS SEKDMIRQMM IKIFRCIEPE LNNLIALGDK IDSFNSLYML VKMSHHVWTA QNVDPASFLS TTLGNVLVTV KRNFDKCISN QIRQMEEVKI SKKSKVGILP FVAEFEEFAG LAESIFKNAE RRGDLDKAYT KLIRGVFVNV EKVANESQKT PRDVVMMENF HHIFATLSRL KISCLEAEKK EAKQKYTDHL QSYVIYSLGQ PLEKLNHFFE GVEARVAQGI REEEVSYQLA FNKQELRKVI KEYPGKEVKK GLDNLYKKVD KHLCEEENLL QVVWHSMQDE FIRQYKHFEG LIARCYPGSG VTMEFTIQDI LDYCSSIAQS H (139-488 aa encoded by BC020650)
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Exocyst complex component 1; Exocyst complex component Sec3; SEC3-like 1; unnamed protein product
Gene Aliases: 2810407P21Rik; A730011E05Rik; BM-012; BM-102; EXOC1; SEC3; SEC3L1; SEC3P
UniProt ID: (Human) Q9NV70, (Mouse) Q8R3S6
Entrez Gene ID: (Human) 55763, (Mouse) 69940, (Rat) 305287
mitotic cytokinesis
exocytosis
Golgi to plasma membrane transport
vesicle docking involved in exocytosis
protein transport
regulation of macroautophagy
defense response to virus
membrane fission
vesicle tethering involved in exocytosis
transport
phosphatidylinositol-mediated signaling
positive regulation of protein secretion
exocyst localization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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