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Product Details
PA5-65195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human EXOC3. Recombinant protein control fragment (Product #RP-104682).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662173
Product Specific Information
Immunogen sequence: VENLKNIFSVP EIVRETQDLI EQGALLQAHR KLMDLECSRD GLMYEQYRMD SGNTRDMTLI HGYFGSTQGL SDELAKQLWM V
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%.
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exocyst complex component 3; Exocyst complex component Sec6; Sec 6 homolog; SEC6-like 1
Gene Aliases: EXOC3; SEC6; SEC6L1; Sec6p
UniProt ID: (Human) O60645
Entrez Gene ID: (Human) 11336
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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