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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
EXOSC9 Fusion Protein Ag19768 (1-351 aa encoded by BC142978) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.27 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MKETPLSNC ERRFLLRAIE EKKRLDGRQT YDYRNIRISF GTDYGCCIVE LGKTRVLGQV SCELVSPKLN RATEGILFFN LELSQMAAPA FEPGRQSDLL VKLNRLMERC LRNSKCIDTE SLCVVAGEKV WQIRVDLHLL NHDGNIIDAA SIAAIVALCH FRRPDVSVQG DEVTLYTPEE RDPVPLSIHH MPICVSFAFF QQGAYLLVDP NEREERVMDG LLVIAMNKHR EICTIQSSGG IMLLKDQVLR CSKIAGVKVA EITELILKAL ENDQKVRKEG GKFGFAESIA NQRITAFKME KAPIDTSDVE EKAEEIIAEA EPPSEVVSTP VLWTPGTAQI GEGVENSWGD LE (1-351 aa encoded by BC142978)
This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Autoantigen PM/Scl 1; Exosome complex component RRP45; exosome complex exonuclease RRP45; Exosome component 9; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; P75 polymyositis-scleroderma overlap syndrome-associated autoantigen; PM/Scl-75; PMSCL autoantigen, 75kD; Polymyositis/scleroderma autoantigen 1; polymyositis/scleroderma autoantigen 1, 75kDa; Polymyositis/scleroderma autoantigen 75 kDa
Gene Aliases: EXOSC9; p5; p6; PM/Scl-75; PMSCL1; RRP45; Rrp45p
UniProt ID: (Human) Q06265
Entrez Gene ID: (Human) 5393
Molecular Function:
RNA metabolism protein
exoribonuclease
nucleic acid metabolism protein
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