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Proteintech
EYA1 Polyclonal Antibody
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Product Details
22658-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EYA1 Fusion Protein Ag18489 (1-300 aa encoded by BC121799)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEMQDLTSP HSRLSGSSES PSGPKLGNSH INSNSMTPNG TEVKTEPMSS SETASTTADG SLNNFSGSAI GSSSFSPRPT HQFSPPQIYP SNRPYPHILP TPSSQTMAAY GQTQFTTGMQ QATAYATYPQ PGQPYGISSY GALWAGIKTE GGLSQSQSPG QTGFLSYGTS FSTPQPGQAP YSYQMQGSSF TTSSGIYTGN NSLTNSSGFN SSQQDYPSYP SFGQGQYAQY YNSSPYPAHY MTSSNTSPTT PSTNATYQLQ EPPSGITSQA VTDPTAEYST IHSPSTPIKD SDSDRLRRGS D (1-300 aa encoded by BC121799)
Target Information
This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EYA1B; EYA1C; Eyes absent; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053; Protein phosphatase EYA1; unnamed protein product
Gene Aliases: BOP; BOR; BOS1; EYA1; OFC1; OTFCS
UniProt ID: (Human) Q99502, (Mouse) P97767
Entrez Gene ID: (Human) 2138, (Mouse) 14048
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
outflow tract morphogenesis
DNA repair
double-strand break repair
chromatin organization
chromatin remodeling
cellular response to DNA damage stimulus
pattern specification process
mesodermal cell fate specification
sensory perception of sound
anatomical structure morphogenesis
organ morphogenesis
response to ionizing radiation
striated muscle tissue development
protein sumoylation
cell differentiation
aorta morphogenesis
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
cell fate commitment
regulation of neuron differentiation
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
neuron fate specification
embryonic skeletal system morphogenesis
semicircular canal morphogenesis
epithelial cell proliferation
positive regulation of epithelial cell proliferation
pharyngeal system development
otic vesicle development
otic vesicle morphogenesis
positive regulation of secondary heart field cardioblast proliferation
cochlea morphogenesis
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
establishment of mitotic spindle orientation
transcription, DNA-templated
regulation of transcription, DNA-templated
protein dephosphorylation
multicellular organism development
chromatin modification
histone dephosphorylation
cellular protein localization
establishment or maintenance of apical/basal cell polarity
peptidyl-tyrosine dephosphorylation
ear morphogenesis
positive regulation of Notch signaling pathway
anatomical structure development
lung epithelial cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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