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Bethyl Laboratories
EYA4 Polyclonal Antibody
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Product Details
IHC-00728
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 100 and 150 of human eyes absent homolog 4.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, X. tropicalis, Bovine, Dog, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and Naked mole rat
Target Information
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ78N10.1 (eyes absent); Eyes absent homolog 4; eyes absent homolog 4 (Drosophila) isoform EYA4_1; eyes absent homolog 4 (Drosophila) isoform EYA4_2; eyes absent-like protein 4; Protein phosphatase EYA4; unnamed protein product
Gene Aliases: CMD1J; DFNA10; EYA4
UniProt ID: (Human) O95677
Entrez Gene ID: (Human) 2070
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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